Haemoglobin variants in mice

Liquid Nitrogen Storage of Haemoglobin Variants.

Received for publication 26 April 1963. is thawed immediately after freezing a precipitate of denatured protein can be seen in the solution. We have recently been investigating the storage of human red cells in liquid nitrogen for serological purposes (Huntsman, Hum, Ikin, Lehmann, and Liddell, 1962). We thought that this technique might be useful for the preservation of haemoglobin as well as ...

The haemoglobin types of mice.

The haemoglobin types of 27 inbred strains of mice have been determined. Besides the common types, Hbb-s and Hbb-p, 2 strains were found with Hbb-p. Affinity between strains with the Hbb-p type and asiatic mice seems likely. The influence of storage on the polymerisation of Hbb-d and Hbb-p, the possibility of distinguishing between homo- and heterozygote Hbb types, and the possible existence o...

Inherited haemoglobin variants in a South African population.

We present the findings of a survey to determine the prevalence of inherited haemoglobin disorders in the Coloured (mixed ethnic origin) population of South Africa. A variety of haemoglobins was found. Of the structural variants, Hb E and Hb S were the most common, the former probably originating from South-East Asia and the latter from East Africa and possibly Madagascar. The alpha+ (-alpha) t...

Scenario of haemoglobin variants in Central-East coast of India

Haemoglobinopathies are the most common monogenic inherited disorders of erythrocytes. Carriers of haemoglobinopathies are partially protected against morbidity and mortality of falciparum malaria, resulting in their higher prevalence in tropical countries. Estimates in India show 3–17% prevalence of β-thalassaemia, but its magnitude in the Central-East coast of India, especially in Orissa is n...

Detection Of Abnormal Haemoglobin Variants By HPLC Method